Sensing pH, DNA and proteins

Bio sensor



We simulate bio sensors that consist of a semiconductor that is connected to a "bio material", e.g. a charged molecule in a liquid (electrolyte).
An electrical or optical signal in the semiconductor is generated to detect DNA, proteins or the pH value.
The semiconductor can be, for instance, a GaN/AlGaN HEMT, a silicon-on-insulator (SOI) transistor or a nanowire.
More information: Bio chips


  • self-consistent Schrödinger, Poisson-Boltzmann and current equations for semiconductor/electrolyte systems
  • 1D, 2D, 3D
  • self-consistent Henderson-Hasselbalch equation for concentration of buffer ions
  • site-binding model for interface charges